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안소윤 ( ) - 지산전문대학 물리치료과
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Abstract
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The purpose of this study is to investigate the effects of the low power Helium Neon-Infra Red(HeNe-IR) laser on wound healing in rat. The thirty Sprague-Dawley adult female and male rats were assigned to the experimental and control groups. Each rat was anesthetized with pentobarbital sodium, and three full-thickness incisions with 12mm length were made on the back of the half of the rats and three deep second degree burns were made on the back of the remainder of the rats. From 24 hours after being injured, the rats of the experimental laser group were irradiated with the 157mW electric power HeNe-IR laser for 2 minutes every day. The rats were sacrificed and the wound parts of its were incised 10th day after the beginning of wound treatment with laser irradiation. The incised wound parts were processed appropriately for the light microscopic and electron microscopic examination. The length of incised wound was measured with microcaliper before the wound part was incised. There was a significant decrease in the length of the incised wound of the experimental laser group, compared with that of control group 10th day(p<0.01) after 1 surgery. Through the . histological examination of the wound site, the more rapid epithelialization and collagen formation in experimental groups were showed, compared with control group. The histological results were analyzed and summarized as the follows;
The chronic inflammatory cells are oberved and the necrosis of the collagen fibers are partially observed in control group on the 10th day. The dermis of the laser reveals relatively compactly arranged collgen bundles with the mature collagen fibers on the 10th day. The Most of proliferated collagen fibrils are found to be compact and regular in electron micrograph of burn skin of the laser treatment group on the 10th day but the
interstitial eadema and some inflammatory cells are found in the control group. 11 The above results suggest that through the visual and histological examination the epithelized epithelium and the proliferation of the collagen fibers in the dermis occur very
effectively with the low power laser treatment in the incised wound healing and the burn wound healing.
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KeyWords
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원문 및 링크아웃 정보
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등재저널 정보
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